838: The effect of standardizing treatment when managing neonatal abstinence syndrome

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Treatment of neonatal abstinence syndrome.

Neonatal abstinence syndrome (NAS) is suffered by infants withdrawing from substances on which they have become physically dependent after in utero exposure. They may require prolonged treatment and spend weeks or even months in hospital. A wide range of drugs have been used to treat NAS. The efficacy of few, however, have been adequately investigated. Evidence suggests that opioids are the mos...

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Neonatal Abstinence Syndrome: Presentation and Treatment Considerations.

The increase in opioid use among the general population is reflected in pregnant women and neonatal abstinence syndrome (NAS) statistics. This increase has produced an unprecedented focus on NAS from both the political-judicial sphere and the medical community. Under the banner of fetal protection, judges and prosecutors have implemented punitive approaches against women who use prescribed and ...

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Neonatal abstinence syndrome after maternal methadone treatment.

Thirty two infants born to mothers taking methadone and 32 matched controls were studied to determine the incidence, timing, and frequency of persistence of withdrawal signs in infants born to maternal methadone users. Twelve (37%) infants received treatment for symptoms of withdrawal. The median length of time from birth to initiation of treatment was 23 hours (range 15-64 hours), the median l...

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Neonatal Abstinence Syndrome (NAS; Neonatal Withdrawal) — Pathophysiology and Treatment

Neonatal abstinence syndrome is characterized by the onset of withdrawal symptoms in a neonate due to prenatal or postnatal exposure to illegal drugs or prescription drugs. The clinical presentation is usually dependent on the duration and time of exposure to the drug and not the drug itself. Meconium analysis or umbilical cord testing are the gold standard for the diagnosis of neonatal abstine...

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Buprenorphine for the Treatment of the Neonatal Abstinence Syndrome.

BACKGROUND Current pharmacologic treatment of the neonatal abstinence syndrome with morphine is associated with a lengthy duration of therapy and hospitalization. Buprenorphine may be more effective than morphine for this indication. METHODS In this single-site, double-blind, double-dummy clinical trial, we randomly assigned 63 term infants (≥37 weeks of gestation) who had been exposed to opi...

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ژورنال

عنوان ژورنال: American Journal of Obstetrics and Gynecology

سال: 2017

ISSN: 0002-9378

DOI: 10.1016/j.ajog.2016.11.747